منابع مشابه
DIHYDROXYACETONE STUDIES: II. Its Respiratory and Carbohydrate Metabolism in Diabetes Mellitus.
In the first paper (1) it was shown that in normal persons dihydroxyacetone given by mouth in 25 or 50 gram doses caused a more rapid and a greater carbohydrate combustion than the same dose of glucose. The elevation of the total metabolism was more marked after the dihydroxyacetone and there was little if any increment increase in the blood sugar. In this report similar studies have been appli...
متن کاملMultienzyme system for dihydroxyacetone phosphate-dependent aldolase catalyzed C-C bond formation from dihydroxyacetone.
A multienzyme system composed by recombinant dihydroxyacetone kinase from Citrobacter freundii, fuculose-1-phosphate aldolase and acetate kinase, allows a practical one-pot C-C bond formation catalysed by dihydroxyacetone phosphate-dependent aldolases from dihydroxyacetone and an aldehyde.
متن کاملExclusive localization in peroxisomes of dihydroxyacetone phosphate acyltransferase and alkyl-dihydroxyacetone phosphate synthase in rat liver.
Dihydroxyacetone phosphate acyl transferase (DHAP-AT), alkyl dihydroxyacetone phosphate synthase (alkyl-DHAP-synthase), and glycerol-3-phosphate acyltransferase (GPAT) activities were investigated under optimal assay conditions using highly purified organelle preparations. The data presented clearly indicate that GPAT activity was mainly localized in mitochondria and microsomes, whereas DHAP-AT...
متن کاملDihydroxyacetone metabolism in Haloferax volcanii
Dihydroxyacetone (DHA) is a ketose sugar that can be produced by oxidizing glycerol. DHA in the environment is taken up and phosphorylated to DHA-phosphate by glycerol kinase or DHA kinase. In hypersaline environments, it is hypothesized that DHA is produced as an overflow product from glycerol utilization by organisms such as Salinibacter ruber. Previous research has demonstrated that the halo...
متن کاملDihydroxyacetone induced autophagy in African trypanosomes.
Dihydroxyacetone (DHA) was examined to explore its trypanocidal activity. The compound is easily taken up by trypanosomes via its aquaglyceroporins but is not converted to a glycolytic intermediate due to the lack of a respective kinase. Investigating the DHA-induced cell death it became evident that parasites die by autophagy rather than by necrosis or apoptosis. Since autophagy is not well st...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1926
ISSN: 0021-9738
DOI: 10.1172/jci100063